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Cancer-Associated PIK3CA Mutations in Overgrowth Disorders

PIK3CA is one of the most commonly mutated genes in solid cancers. PIK3CA mutations are also found in benign overgrowth syndromes, collectively known as PIK3CA-related overgrowth spectrum (PROS). As in cancer, PIK3CA mutations in PROS arise postzygotically, but unlike in cancer, these mutations aris...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Trends Mol Med
Päätekijät: Madsen, Ralitsa R., Vanhaesebroeck, Bart, Semple, Robert K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier Science Ltd 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6185869/
https://ncbi.nlm.nih.gov/pubmed/30197175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2018.08.003
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