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AGING CHANGES MICROBIOME AFFECTING CROSSTALK AND ACTIVITY OF MONOCYTES AND B1A CELLS
Aging significantly dysregulates function and composition of immune cells. We recently reported that elderly humans, macaques and mice accumulate 4-1BBL+TNF+MHC class-IHi CD86Hi B cells 1. These cells (4BL cells) are innate B1a cells activated by monocytes 2. In response to microbiota change in agin...
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Pubblicato in: | Innov Aging |
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Autore principale: | |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Oxford University Press
2017
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6185043/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.3864 |
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