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Efficient flexible backbone protein–protein docking for challenging targets

MOTIVATION: Binding-induced conformational changes challenge current computational docking algorithms by exponentially increasing the conformational space to be explored. To restrict this search to relevant space, some computational docking algorithms exploit the inherent flexibility of the protein...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Marze, Nicholas A, Roy Burman, Shourya S, Sheffler, William, Gray, Jeffrey J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6184633/
https://ncbi.nlm.nih.gov/pubmed/29718115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty355
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