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ADVANCING PREDICTIVE AND PRECISION MEDICINE USING HUMAN NEURAL ORGANOID MODELS OF BRAIN DISEASES
We have engineered neural organoids (containing the retina, cortex, midbrain, hindbrain, brain stem and spinal cord) from normal, Alzheimer’s disease (APP gene duplication) and tuberous sclerosis (TSC2Arg1743Gln) patient skin cells. Whole genome transcriptomic results remarkably show comprehensive a...
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| Publicado no: | Innov Aging |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6184059/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.4813 |
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