Effects of a single long-acting muscarinic antagonist agent and a long-acting muscarinic antagonist/long-acting β2-adrenoceptor agonist combination on lung function and symptoms in untreated COPD patients in Japan

BACKGROUND: A large body of evidence suggests that long-acting β2-adrenoceptor agonist (LABA)/long-acting muscarinic antagonist (LAMA) combinations induce a strong synergistic bronchodilatory effect in human isolated airways. Moreover, a recent post hoc analysis demonstrated clinical synergism betwe...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Chron Obstruct Pulmon Dis
Hauptverfasser: Yamada, Hideyasu, Hida, Norihito, Hizawa, Nobuyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2018
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6183692/
https://ncbi.nlm.nih.gov/pubmed/30349222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S179285
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