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ADVANCED GLYCATION ENDPRODUCTS (AGES) AT THE NEXUS OF AGING, DIABETES, AND NEURODEGENERATION
Aging and hyperglycemia results in an accumulation of a series of reactive α-dicarbonyl compounds (α-DCs, e.g. glyoxal/GO, methylglyoxal/MGO, 3-deoxyglucosone/3DG) and α-DC-derived metabolites, called advanced glycation end products (AGEs). AGEs form due to the reaction of α-DCs with proteins, lipid...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Innov Aging |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Oxford University Press
2017
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6183522/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.4404 |
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