Establishment of a novel platform cell line for efficient and precise evaluation of T cell receptor functional avidity

Adoptive T-cell therapy with T cell receptor (TCR) -engineered T cells is an attractive strategy for cancer treatment and the success in this therapy is dependent on the functional avidity of the transduced TCRs against targeted tumor antigens. Therefore, the establishment of the methodology of the...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Morimoto, Soyoko, Fujiki, Fumihiro, Kondo, Kenta, Nakajima, Hiroko, Kobayashi, Yoshiki, Inatome, Miki, Aoyama, Nao, Nishida, Yuya, Tsuboi, Akihiro, Oka, Yoshihiro, Nishida, Sumiyuki, Nakata, Jun, Hosen, Naoki, Oji, Yusuke, Sugiyama, Haruo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2018
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6183340/
https://ncbi.nlm.nih.gov/pubmed/30344927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26139
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