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Complex formation between platelet-derived growth factor receptor β and transforming growth factor β receptor regulates the differentiation of mesenchymal stem cells into cancer-associated fibroblasts

Cancer-associated fibroblasts (CAFs) have recently gained attention as potent targets in cancer therapy because they are a crucial component of the tumor microenvironment and promote the growth and invasion of cancer cells. CAFs differentiate from fibroblasts, mesenchymal stem cells (MSCs), epitheli...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Aoto, Kaori, Ito, Kousei, Aoki, Shigeki
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6183337/
https://ncbi.nlm.nih.gov/pubmed/30344924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26124
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