Rational design of heat stable lyophilized rotavirus vaccine formulations

To develop a safe and efficacious heat-stable rotavirus vaccine, new lyophilized formulations were developed using rotavirus serotypes constituting RotaTeq®. A series of formulation compositions, differing in buffering agents, bulking agents, cryoprotectants, amino acids and divalent cations, were s...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Madan, Madhu, Sikriwal, Deepa, Sharma, Gaurav, Shukla, Nidhi, Mandyal, Ashwani Kumar, Kale, Sachin, Gill, Davinder
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6183320/
https://ncbi.nlm.nih.gov/pubmed/29953317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2018.1487499
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