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A randomized, single-blind, single-dose study to assess the pharmacokinetic equivalence of the biosimilar ABP 215 and bevacizumab in healthy Japanese male subjects

PURPOSE: Analytic, pharmacokinetic (PK), and clinical similarity between the biosimilar ABP 215 and bevacizumab has previously been demonstrated in global studies. Here we present a phase 1 study in healthy adult Japanese men. METHODS: This study was a randomized, single-blind, single-dose, parallel...

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Bibliografski detalji
Izdano u:Cancer Chemother Pharmacol
Glavni autori: Hanes, Vladimir, Chow, Vincent, Pan, Zhiying, Markus, Richard
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182752/
https://ncbi.nlm.nih.gov/pubmed/30269275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-018-3695-4
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