Phase Ib study of irinotecan and ramucirumab for advanced gastric cancer previously treated with fluoropyrimidine with/without platinum and taxane

PURPOSE: Optimal salvage chemotherapy for patients with treated advanced/metastatic gastric cancer (AGC) is unknown. Irinotecan is commonly used in Japan. Ramucirumab, a human IgG-1 monoclonal antibody targeting the extracellular domain of VEGF receptor 2, is the first molecularly targeted agent pro...

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Dettagli Bibliografici
Pubblicato in:Cancer Chemother Pharmacol
Autori principali: Satake, Hironaga, Sagawa, Tamotsu, Fujikawa, Koshi, Hatachi, Yukimasa, Yasui, Hisateru, Kotaka, Masahito, Kato, Takeshi, Tsuji, Akihito
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2018
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182742/
https://ncbi.nlm.nih.gov/pubmed/30167847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-018-3678-5
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