A protein–protein interaction underlies the molecular basis for substrate recognition by an adenosine-to-inosine RNA-editing enzyme

Adenosine deaminases that act on RNA (ADARs) convert adenosine to inosine within double-stranded regions of RNA, resulting in increased transcriptomic diversity, as well as protection of cellular double-stranded RNA (dsRNA) from silencing and improper immune activation. The presence of dsRNA-binding...

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Опубликовано в: :Nucleic Acids Res
Главные авторы: Rajendren, Suba, Manning, Aidan C, Al-Awadi, Haider, Yamada, Kentaro, Takagi, Yuichiro, Hundley, Heather A
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
Предметы:
Nucleic Acid Enzymes
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182170/
https://ncbi.nlm.nih.gov/pubmed/30202880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky800
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