Signaling specificity in the c-di-GMP-dependent network regulating antibiotic synthesis in Lysobacter

Enzymes controlling intracellular second messengers in bacteria, such as c-di-GMP, often affect some but not other targets. How such specificity is achieved is understood only partially. Here, we present a novel mechanism that enables specific c-di-GMP-dependent inhibition of the antifungal antibiot...

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Publicado en:Nucleic Acids Res
Autores principales: Xu, Gaoge, Han, Sen, Huo, Cuimei, Chin, Ko-Hsin, Chou, Shan-Ho, Gomelsky, Mark, Qian, Guoliang, Liu, Fengquan
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182147/
https://ncbi.nlm.nih.gov/pubmed/30202891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky803
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