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Hydroxyurea Treated β-Thalassemia Children Demonstrate a Shift in Metabolism Towards Healthy Pattern

Augmentation of fetal hemoglobin (HbF) production has been an enduring therapeutic objective in β-thalassemia patients for which hydroxyurea (HU) has largely been the drug of choice and the most cost-effective approach. A serum metabolomics study on 40 patients with β-thalassemia prior to and after...

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Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Iqbal, Ayesha, Ansari, Saqib Hussain, Parveen, Sadia, Khan, Ishtiaq Ahmad, Siddiqui, Amna Jabbar, Musharraf, Syed Ghulam
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182004/
https://ncbi.nlm.nih.gov/pubmed/30310134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33540-6
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