Non-neutralizing antibodies elicited by recombinant Lassa–Rabies vaccine are critical for protection against Lassa fever

Lassa fever (LF), caused by Lassa virus (LASV), is a viral hemorrhagic fever for which no approved vaccine or potent antiviral treatment is available. LF is a WHO priority disease and, together with rabies, a major health burden in West Africa. Here we present the development and characterization of...

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Vydáno v:Nat Commun
Hlavní autoři: Abreu-Mota, Tiago, Hagen, Katie R., Cooper, Kurt, Jahrling, Peter B., Tan, Gene, Wirblich, Christoph, Johnson, Reed F., Schnell, Matthias J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181965/
https://ncbi.nlm.nih.gov/pubmed/30310067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06741-w
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