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Polynucleotide phosphorylase: Not merely an RNase but a pivotal post-transcriptional regulator

Almost 60 years ago, Severo Ochoa was awarded the Nobel Prize in Physiology or Medicine for his discovery of the enzymatic synthesis of RNA by polynucleotide phosphorylase (PNPase). Although this discovery provided an important tool for deciphering the genetic code, subsequent work revealed that the...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Cameron, Todd A., Matz, Lisa M., De Lay, Nicholas R.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181284/
https://ncbi.nlm.nih.gov/pubmed/30307990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007654
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