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Pharmacometric Applications and Challenges in the Development of Therapeutic Antibodies in Immuno-Oncology
PURPOSE OF REVIEW: Monoclonal antibodies targeting key checkpoints in immune stimulatory pathways have over the last years become the mainstay of cancer immunotherapy. This article provides a brief review of the application and key impact of pharmacometrics and quantitative clinical pharmacology app...
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| 出版年: | Curr Pharmacol Rep |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6181227/ https://ncbi.nlm.nih.gov/pubmed/30319936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40495-018-0142-5 |
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