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Recombinant protein susceptibility to proteolysis in the plant cell secretory pathway is pH‐dependent

Cellular engineering approaches have been proposed to mitigate unintended proteolysis in plant protein biofactories, involving the design of protease activity‐depleted environments by gene silencing or in situ inactivation with accessory protease inhibitors. Here, we assessed the impact of influenza...

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Detalhes bibliográficos
Publicado no:Plant Biotechnol J
Main Authors: Jutras, Philippe V., Goulet, Marie‐Claire, Lavoie, Pierre‐Olivier, D'Aoust, Marc‐André, Sainsbury, Frank, Michaud, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181212/
https://ncbi.nlm.nih.gov/pubmed/29618167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pbi.12928
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