Bordetella bronchiseptica Colonization Limits Efficacy, but Not Immunogenicity, of Live-Attenuated Influenza Virus Vaccine and Enhances Pathogenesis After Influenza Challenge

Intranasally administered live-attenuated influenza virus (LAIV) vaccines provide significant protection against heterologous influenza A virus (IAV) challenge. However, LAIV administration can modify the bacterial microbiota in the upper respiratory tract, including alterations in species that caus...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hughes, Holly R., Brockmeier, Susan L., Loving, Crystal L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180198/
https://ncbi.nlm.nih.gov/pubmed/30337924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02255
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