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PKMζ in the nucleus accumbens acts to dampen cocaine seeking

The constitutively active, atypical protein kinase C, protein kinase M-ζ (PKMζ), is exclusively expressed in the brain and its expression increases following exposure to drugs of abuse. However, the limitations of currently available tools have made it difficult to examine the role of PKMζ in cocain...

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Pubblicato in:Neuropsychopharmacology
Autori principali: McGrath, Anna G., Lenz, Jeffrey D., Briand, Lisa A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180118/
https://ncbi.nlm.nih.gov/pubmed/30111812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0170-1
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