DNA-methylation-mediated silencing of miR-486-5p promotes colorectal cancer proliferation and migration through activation of PLAGL2/IGF2/β-catenin signal pathways

As one of the most common cancers worldwide, colorectal cancer (CRC) causes a large number of mortality annually. Aberrant expression of microRNAs (miRNAs) is significantly associated with the initiation and development of CRC. Further investigations regarding the regulatory mechanism of miRNAs is w...

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Publicat a:Cell Death Dis
Autors principals: Liu, Xiangxiang, Chen, Xiaoxiang, Zeng, Kaixuan, Xu, Mu, He, Bangshun, Pan, Yuqin, Sun, Huiling, Pan, Bei, Xu, Xueni, Xu, Tao, Hu, Xiuxiu, Wang, Shukui
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180105/
https://ncbi.nlm.nih.gov/pubmed/30305607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1105-9
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