Targeted Therapy in Advanced Thyroid Cancer to Resensitize Tumors to Radioactive Iodine

CONTEXT: Many differentiated thyroid cancers (DTC) dedifferentiate and become radioactive iodine (RAI)–refractory (RAIR) with worse outcomes. Targeted therapy (TTx) may downregulate MAPK signaling and sensitize tumors to RAI. OBJECTIVE: We describe patients with RAIR DTC receiving TTx with demonstra...

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Pubblicato in:J Clin Endocrinol Metab
Autori principali: Jaber, Tania, Waguespack, Steven G, Cabanillas, Maria E, Elbanan, Mohamed, Vu, Thinh, Dadu, Ramona, Sherman, Steven I, Amit, Moran, Santos, Elmer B, Zafereo, Mark, Busaidy, Naifa L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2018
Soggetti:
Clinical Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6179172/
https://ncbi.nlm.nih.gov/pubmed/30032208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2018-00612
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