A Chemical, Genetic, and Structural Analysis of the Nuclear Bile Acid Receptor FXR

The farnesoid X receptor (FXR) functions as a bile acid (BA) sensor coordinating cholesterol metabolism, lipid homeostasis, and absorption of dietary fats and vitamins. However, BAs are poor reagents for characterizing FXR functions due to multiple receptor independent properties. Accordingly, using...

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Udgivet i:Mol Cell
Main Authors: Downes, Michael, Verdecia, Mark A., Roecker, A.J., Hughes, Robert, Hogenesch, John B., Kast-Woelbern, Heidi R., Bowman, Marianne E., Ferrer, Jean-Luc, Anisfeld, Andrew M., Edwards, Peter A., Rosenfeld, John M., Alvarez, Jacqueline G.A., Noel, Joseph P., Nicolaou, K.C, Evans, Ronald M.
Format: Artigo
Sprog:Inglês
Udgivet: 2003
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6179153/
https://ncbi.nlm.nih.gov/pubmed/12718892
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