Glucose and glutamine availability regulate HepG2 transcriptional responses to low oxygen

Background: Little is known about the impact of nutrients on cellular transcriptional responses, especially in face of environmental stressors such as oxygen deprivation. Hypoxia-inducible factors (HIF) coordinate the expression of genes essential for adaptation to oxygen-deprived environments. A se...

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Veröffentlicht in:Wellcome Open Res
Hauptverfasser: Lai, Alvina G., Forde, Donall, Chang, Wai Hoong, Yuan, Fang, Zhuang, Xiaodong, Orbegozo Rubio, Claudia, Song, Chun-Xiao, McKeating, Jane A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: F1000 Research Limited 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178907/
https://ncbi.nlm.nih.gov/pubmed/30345392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.14839.1
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