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Mahanimbine Exerts Anticancer Effects on Human Pancreatic Cancer Cells by Triggering Cell Cycle Arrest, Apoptosis, and Modulation of AKT/Mammalian Target of Rapamycin (mTOR) and Signal Transducer and Activator of Transcription 3 (STAT3) Signalling Pathways
BACKGROUND: Pancreatic cancer causes tremendous mortality across the globe mainly due to late diagnosis and unavailability of efficient chemotheruptic agents. In the current study the anticancer potential of a plant derived alkaloid, Mahanimbine, was examined against a panel of pancreatic cancer cel...
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| Published in: | Med Sci Monit |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
International Scientific Literature, Inc.
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6178883/ https://ncbi.nlm.nih.gov/pubmed/30273298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.911013 |
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