Crosstalk between BPA and FXRα Signaling Pathways Lead to Alterations of Undifferentiated Germ Cell Homeostasis and Male Fertility Disorders

Several studies have reported an association between the farnesoid X receptor alpha (FXRα) and estrogenic signaling pathways. Fxrα could thus be involved in the reprotoxic effects of endocrine disruptors such as bisphenol-A (BPA). To test this hypothesis, mice were exposed to BPA and/or stigmasterol...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Sèdes, Lauriane, Desdoits-Lethimonier, Christèle, Rouaisnel, Betty, Holota, Hélène, Thirouard, Laura, Lesne, Laurianne, Damon-Soubeyrand, Christelle, Martinot, Emmanuelle, Saru, Jean-Paul, Mazaud-Guittot, Séverine, Caira, Françoise, Beaudoin, Claude, Jégou, Bernard, Volle, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178796/
https://ncbi.nlm.nih.gov/pubmed/30245210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.08.018
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