Metastatic adrenocortical carcinoma displays higher mutation rate and tumor heterogeneity than primary tumors

Adrenocortical cancer (ACC) is a rare cancer with poor prognosis and high mortality due to metastatic disease. All reported genetic alterations have been in primary ACC, and it is unknown if there is molecular heterogeneity in ACC. Here, we report the genetic changes associated with metastatic ACC c...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Gara, Sudheer Kumar, Lack, Justin, Zhang, Lisa, Harris, Emerson, Cam, Margaret, Kebebew, Electron
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178360/
https://ncbi.nlm.nih.gov/pubmed/30301885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06366-z
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