Intranasal delivery of a Fas-blocking peptide attenuates Fas-mediated apoptosis in brain ischemia

Ischemic stroke-induced neuronal cell death results in the permanent disabling of brain function. Apoptotic mechanisms are thought to play a prominent role in neuronal injury and ample evidence implicates Fas signaling in mediating cell death. In this study, we describe the neuroprotective effects o...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Ullah, Irfan, Chung, Kunho, Oh, Jungju, Beloor, Jagadish, Bae, Sumin, Lee, Sangah Clara, Lee, Minhyung, Kumar, Priti, Lee, Sang-Kyung
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178348/
https://ncbi.nlm.nih.gov/pubmed/30301943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33296-z
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