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Activator protein-1 contributes to the NaCl-induced expression of VEGF and PlGF in RPE cells

PURPOSE: Systemic hypertension is a risk factor of neovascular age-related macular degeneration; consumption of dietary salt resulting in extracellular hyperosmolarity is a main cause of hypertension. Extracellular hyperosmolarity was shown to induce expression of angiogenic growth factors, such as...

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Detalhes bibliográficos
Publicado no:Mol Vis
Main Authors: Kleiner, Jana, Hollborn, Margrit, Wiedemann, Peter, Bringmann, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178337/
https://ncbi.nlm.nih.gov/pubmed/30310263
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