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Standardization and application of a modified RFLP-PCR methodology for analysis of polymorphisms linked to treatment resistance in Ancylostoma braziliense

BACKGROUND: Single nucleotide polymorphisms (SNPs) in codons 167, 198 and 200 of the beta-tubulin isotype 1 gene are associated with benzimidazoles resistance in many helminths. Codon 167 mutation has never been described in hookworms; however, polymorphisms in codons 198 and 200 have been described...

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Vydáno v:Parasit Vectors
Hlavní autoři: Furtado, Luis Fernando Viana, Magalhães, João Guilherme Scarpelli, Rabelo, Élida Mara Leite
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178248/
https://ncbi.nlm.nih.gov/pubmed/30301454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-018-3125-9
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