Dynamic MAPK/ERK Activity Sustains Nephron Progenitors through Niche Regulation and Primes Precursors for Differentiation

The in vivo niche and basic cellular properties of nephron progenitors are poorly described. Here we studied the cellular organization and function of the MAPK/ERK pathway in nephron progenitors. Live-imaging of ERK activity by a Förster resonance energy transfer biosensor revealed a dynamic activat...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Stem Cell Reports
Huvudupphovsmän: Ihermann-Hella, Anneliis, Hirashima, Tsuyoshi, Kupari, Jussi, Kurtzeborn, Kristen, Li, Hao, Kwon, Hyuk Nam, Cebrian, Cristina, Soofi, Abdul, Dapkunas, Arvydas, Miinalainen, Ilkka, Dressler, Gregory R., Matsuda, Michiyuki, Kuure, Satu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178244/
https://ncbi.nlm.nih.gov/pubmed/30220628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.08.012
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk