STAT2 Signaling Regulates Macrophage Phenotype During Influenza and Bacterial Super-Infection

Influenza is a common respiratory virus that infects between 5 and 20% of the US population and results in 30,000 deaths annually. A primary cause of influenza-associated death is secondary bacterial pneumonia. We have previously shown that influenza induces type I interferon (IFN)-mediated inhibiti...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Gopal, Radha, Lee, Benjamin, McHugh, Kevin J., Rich, Helen E., Ramanan, Krishnaveni, Mandalapu, Sivanarayana, Clay, Michelle E., Seger, Philip J., Enelow, Richard I., Manni, Michelle L., Robinson, Keven M., Rangel-Moreno, Javier, Alcorn, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178135/
https://ncbi.nlm.nih.gov/pubmed/30337919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02151
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