Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling

The RNA-binding protein Musashi 2 (MSI2) has emerged as an important regulator in cancer initiation, progression, and drug resistance. Translocations and deregulation of the MSI2 gene are diagnostic of certain cancers, including chronic myeloid leukemia (CML) with translocation t(7;17), acute myeloi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Duggimpudi, Sujitha, Kloetgen, Andreas, Maney, Sathish Kumar, Münch, Philipp C., Hezaveh, Kebria, Shaykhalishahi, Hamed, Hoyer, Wolfgang, McHardy, Alice C., Lang, Philipp A., Borkhardt, Arndt, Hoell, Jessica I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177596/
https://ncbi.nlm.nih.gov/pubmed/30126842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002243
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