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Cryo-EM structure of the hibernating Thermus thermophilus 100S ribosome reveals a protein-mediated dimerization mechanism

In response to cellular stresses bacteria conserve energy by dimerization of ribosomes into inactive hibernating 100S ribosome particles. Ribosome dimerization in Thermus thermophilus is facilitated by hibernation-promoting factor (TtHPF). In this study we demonstrate high sensitivity of Tt100S form...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Flygaard, Rasmus Kock, Boegholm, Niels, Yusupov, Marat, Jenner, Lasse B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177447/
https://ncbi.nlm.nih.gov/pubmed/30301898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06724-x
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