An optogenetic toolbox of LOV-based photosensitizers for light-driven killing of bacteria

Flavin-binding fluorescent proteins (FPs) are genetically encoded in vivo reporters, which are derived from microbial and plant LOV photoreceptors. In this study, we comparatively analyzed ROS formation and light-driven antimicrobial efficacy of eleven LOV-based FPs. In particular, we determined sin...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Endres, Stephan, Wingen, Marcus, Torra, Joaquim, Ruiz-González, Rubén, Polen, Tino, Bosio, Gabriela, Bitzenhofer, Nora Lisa, Hilgers, Fabienne, Gensch, Thomas, Nonell, Santi, Jaeger, Karl-Erich, Drepper, Thomas
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177443/
https://ncbi.nlm.nih.gov/pubmed/30301917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33291-4
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