Apatinib-induced protective autophagy and apoptosis through the AKT–mTOR pathway in anaplastic thyroid cancer

Apatinib, an inhibitor of vascular endothelial growth factor receptor-2, has been shown to promote anti-cancer action across a wide range of malignancies, including gastric, lung, and breast cancers. Our previous study showed that apatinib increases apoptosis in anaplastic thyroid carcinoma (ATC), b...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Feng, Haoran, Cheng, Xi, Kuang, Jie, Chen, Lingxie, Yuen, Stanley, Shi, Minmin, Liang, Juyong, Shen, Baiyong, Jin, Zhijian, Yan, Jiqi, Qiu, Weihua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177436/
https://ncbi.nlm.nih.gov/pubmed/30301881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1054-3
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