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Immune-checkpoint inhibitors for combating T-cell dysfunction in cancer

Under normal conditions, the immune system responds effectively to both external and internal threats without damaging healthy tissues. Cells undergoing a neoplastic transformation are one such threat. An efficient activation of T cells is enabled by T-cell receptor (TCR) interactions with antigen-p...

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Bibliografiske detaljer
Udgivet i:Onco Targets Ther
Main Authors: Grywalska, Ewelina, Pasiarski, Marcin, Góźdź, Stanisław, Roliński, Jacek
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177399/
https://ncbi.nlm.nih.gov/pubmed/30323625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S150817
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