Blood–brainbarrier disruption dictates nanoparticle accumulation following experimental brain injury

Clinically, traumatic brain injury (TBI) results in complex heterogeneous pathology that cannot be recapitulated in single pre-clinical animal model. Therefore, we focused on evaluating utility of nanoparticle (NP)-based therapeutics following three diffuse-TBI models: mildclosed-head injury (mCHI),...

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Bibliografiske detaljer
Udgivet i:Nanomedicine
Main Authors: Bharadwaj, Vimala N., Rowe, Rachel K., Harrison, Jordan, Wu, Chen, Anderson, Trent R., Lifshitz, Jonathan, Adelson, P. David, Kodibagkar, Vikram D., Stabenfeldt, Sarah E.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177306/
https://ncbi.nlm.nih.gov/pubmed/29933022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2018.06.004
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