IgM cleavage by Streptococcus suis reduces IgM bound to the bacterial surface and is a novel complement evasion mechanism

Streptococcus suis (S. suis) causes meningitis, arthritis and endocarditis in piglets. The aim of this study was to characterize the IgM degrading enzyme of S. suis (Ide(Ssuis)) and to investigate the role of IgM cleavage in evasion of the classical complement pathway and pathogenesis. Targeted muta...

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Detalhes bibliográficos
Publicado no:Virulence
Main Authors: Rungelrath, Viktoria, Weiße, Christine, Schütze, Nicole, Müller, Uwe, Meurer, Marita, Rohde, Manfred, Seele, Jana, Valentin-Weigand, Peter, Kirschfink, Michael, Beineke, Andreas, Schrödl, Wieland, Bergmann, René, Baums, Christoph Georg
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177247/
https://ncbi.nlm.nih.gov/pubmed/30001174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2018.1496778
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