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A type 2 diabetes disease module with a high collective influence for Cdk2 and PTPLAD1 is localized in endosomes

Despite the identification of many susceptibility genes our knowledge of the underlying mechanisms responsible for complex disease remains limited. Here, we identified a type 2 diabetes disease module in endosomes, and validate it for functional relevance on selected nodes. Using hepatic Golgi/endos...

詳細記述

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書誌詳細
出版年:PLoS One
主要な著者: Boutchueng-Djidjou, Martial, Belleau, Pascal, Bilodeau, Nicolas, Fortier, Suzanne, Bourassa, Sylvie, Droit, Arnaud, Elowe, Sabine, Faure, Robert L.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177195/
https://ncbi.nlm.nih.gov/pubmed/30300385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205180
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