Prebiotic Supplementation Following Ileocecal Resection in a Murine Model is Associated With a Loss of Microbial Diversity and Increased Inflammation

BACKGROUND: Individuals with Crohn’s disease frequently require ileocecal resection (ICR), and inflammation often recurs in the neoterminal ileum following surgery. Fructooligosaccharide (FOS) is a fermentable prebiotic that stimulates the growth of bifidobacteria and may promote anti-inflammatory a...

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Bibliographic Details
Published in:Inflamm Bowel Dis
Main Authors: Laffin, Michael, Perry, Troy, Park, Heekuk, Hotte, Naomi, Fedorak, Richard N, Thiesen, Aducio, Dicken, Bryan, Madsen, Karen L
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Original Research Articles-Basic Science
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176898/
https://ncbi.nlm.nih.gov/pubmed/29272494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izx033
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