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Intratumoral heterogeneity of oxygen metabolism and neovascularization uncovers 2 survival-relevant subgroups of IDH1 wild-type glioblastoma

BACKGROUND: The intratumoral heterogeneity of oxygen metabolism in combination with variable patterns of neovascularization (NV) as well as reprogramming of energy metabolism affects the landscape of tumor microenvironments (TMEs) in glioblastoma. Knowledge of the hypoxic and perivascular niches wit...

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Publicado en:Neuro Oncol
Main Authors: Stadlbauer, Andreas, Zimmermann, Max, Doerfler, Arnd, Oberndorfer, Stefan, Buchfelder, Michael, Coras, Roland, Kitzwögerer, Melitta, Roessler, Karl
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176796/
https://ncbi.nlm.nih.gov/pubmed/29718366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy066
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