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Chemoenzymatic assembly of mammalian O-mannose glycans

O-Mannose glycans, a family of highly heterogeneous complex glycans account up to 30% of total O-glycans in brain. Previous synthesis and functional studies only focused on the Core M3 O-mannose glycans of α-dystroglycan which are a causative factor for various muscular diseases. In this study, a hi...

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Détails bibliographiques
Publié dans:Angew Chem Int Ed Engl
Auteurs principaux: Meng, Caicai, Sasmal, Aniruddha, Zhang, Yan, Gao, Tian, Liu, Chang-Cheng, Khan, Naazneen, Varki, Ajit, Wang, Fengshan, Cao, Hongzhi
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176721/
https://ncbi.nlm.nih.gov/pubmed/29802667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201804373
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