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Functional profiling of circulating tumor cells with an integrated vortex capture and single-cell protease activity assay
Tumor cells are hypothesized to use proteolytic enzymes to facilitate invasion. Whether circulating tumor cells (CTCs) secrete these enzymes to aid metastasis is unknown. A quantitative and high-throughput approach to assay CTC secretion is needed to address this question. We developed an integrated...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6176626/ https://ncbi.nlm.nih.gov/pubmed/30224472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803884115 |
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