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Regulatory γ1 subunits defy symmetry in functional modulation of BK channels
Structural symmetry is a hallmark of homomeric ion channels. Nonobligatory regulatory proteins can also critically define the precise functional role of such channels. For instance, the pore-forming subunit of the large conductance voltage and calcium-activated potassium (BK, Slo1, or KCa(1.1)) chan...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6176617/ https://ncbi.nlm.nih.gov/pubmed/30224470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804560115 |
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