Eplerenone attenuates myocardial infarction in diabetic rats via modulation of the PI3K-Akt pathway and phosphorylation of GSK-3β

We investigated the effect of eplerenone on myocardial infarcted diabetic rats via modulation of the PI3K/Akt pathway and its downstream target GSK-3β. Diabetes was induced by administration of a single dose of streptozotocin (55 mg/kg IP). Diabetic rats received either eplerenone or PI3k/Akt antago...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Transl Res
Prif Awduron: Mahajan, Umesh B, Chandrayan, Govind, Patil, Chandragouda R, Arya, Dharamvir Singh, Suchal, Kapil, Agrawal, Yogeeta, Ojha, Shreesh, Goyal, Sameer N
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: e-Century Publishing Corporation 2018
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176230/
https://ncbi.nlm.nih.gov/pubmed/30323868
Tagiau: Ychwanegu Tag
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