Cytotoxic T lymphocyte antigen-4 gene polymorphisms and susceptibility to type 1 autoimmune hepatitis in the Tunisian population

Genetic factors and gene polymorphisms leading to the onset of autoimmune response in autoimmune hepatitis (AIH) are still not full elucidated. Since the CTLA-4 molecule is a key modulator of the lymphocytes responses we hypothezied that deficiencies or mutations in the gene encoding CTLA4 protein m...

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Publicat a:Genes Dis
Autors principals: Chaouali, Marwa, Carvalho, Agostinho, Tezeghdenti, Aymen, Ben Azaiez, Mouna, Cunha, Cristina, Ghazouani, Ezzeddine, Kochkar, Radhia
Format: Artigo
Idioma:Inglês
Publicat: Chongqing Medical University 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176120/
https://ncbi.nlm.nih.gov/pubmed/30320190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2017.12.006
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