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Synthetic Light-Activated Ion Channels for Optogenetic Activation and Inhibition

Optogenetic manipulation of cells or living organisms became widely used in neuroscience following the introduction of the light-gated ion channel channelrhodopsin-2 (ChR2). ChR2 is a non-selective cation channel, ideally suited to depolarize and evoke action potentials in neurons. However, its calc...

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Publicat a:Front Neurosci
Autors principals: Beck, Sebastian, Yu-Strzelczyk, Jing, Pauls, Dennis, Constantin, Oana M., Gee, Christine E., Ehmann, Nadine, Kittel, Robert J., Nagel, Georg, Gao, Shiqiang
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176052/
https://ncbi.nlm.nih.gov/pubmed/30333716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00643
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