Overexpression of Wild-Type Human Alpha-Synuclein Causes Metabolism Abnormalities in Thy1-aSYN Transgenic Mice

Parkinson’s disease is a progressive neurodegenerative disorder characterized by loss of dopaminergic neurons, pathological accumulation of alpha-synuclein and motor symptoms, but also by non-motor symptoms. Metabolic abnormalities including body weight loss have been reported in patients and could...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Cuvelier, Elodie, Méquinion, Mathieu, Leghay, Coline, Sibran, William, Stievenard, Aliçia, Sarchione, Alessia, Bonte, Marie-Amandine, Vanbesien-Mailliot, Christel, Viltart, Odile, Saitoski, Kevin, Caron, Emilie, Labarthe, Alexandra, Comptdaer, Thomas, Semaille, Pierre, Carrié, Hélène, Mutez, Eugénie, Gressier, Bernard, Destée, Alain, Chartier-Harlin, Marie-Christine, Belarbi, Karim
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176013/
https://ncbi.nlm.nih.gov/pubmed/30333721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00321
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