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Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing

The ability of proteins to sense membrane curvature is essential to cellular function. All known sensing mechanisms rely on protein domains with specific structural features such as wedge-like amphipathic helices and crescent-shaped BAR domains. Yet many proteins that contain these domains also cont...

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Vydáno v:Nat Commun
Hlavní autoři: Zeno, Wade F., Baul, Upayan, Snead, Wilton T., DeGroot, Andre C. M., Wang, Liping, Lafer, Eileen M., Thirumalai, D., Stachowiak, Jeanne C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175956/
https://ncbi.nlm.nih.gov/pubmed/30297718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06532-3
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